Pathophysiological Mechanisms for Heart Failure with Preserved Ejection Fraction (HF‐pEF): A Mathematical Modeling Analysis

[Heart failure with preserved ejection fraction (HFpEF)].

Heart failure with preserved ejection fraction (HFpEF): a basic and clinical perspective

Up to 50% of patients with heart failure have a relatively normal ejection fraction; this is called “heart failure with preserved ejection fraction” or HFpEF. These patients are more likely to be older, female, hypertensive, obese, or to have metabolic syndrome or atrial fibrillation. They suffer substantial mortality and morbidity, but there are currently no treatments available proven to impr...

Heart Failure With Preserved Ejection Fraction

The Journal of the American Osteopathic Association July 2015 | Vol 115 | No. 7 432 From Henry Ford Wyandotte Downriver Cardiology in Brownstown, Michigan (Dr Rogers); West Suburban Medical Center in Oak Park, Illinois (Dr Gundala); Oakwood Southshore Medical Center in Trenton, Michigan (Dr Ramos); and Elmhurst Memorial Hospital in Illinois (Dr Serajian). Drs Gundala and Ramos are in their thir...

Heart Failure With Preserved Ejection Fraction

Symptomatic heart failure, despite preserved left ventricular (LV) ejection fraction, is a well-recognized phenomenon. This manifestation of diastolic dysfunction is associated with increased morbidity and mortality and can be attributed to a variety of pathogeneses, including diabetes mellitus, hypertension, infiltrative processes, and obesity. Unlike in systolic heart failure, where LV ejecti...

Heart Failure with Preserved Ejection Fraction

1. Demonstrate the association between heart failure with preserved ejection fraction (HFpEF) and survival. 2. Given a patient with heart failure (HF), recognize HFpEF on the basis of clinical signs and symptoms, physical examination, echocardiography, and radiographic findings. 3. Classify patients at high risk of hospitalization and mortality through assessing risk factors, clinical presentat...